Man ought to know that from the brain and from the brain only, arise our pleasures, joys, laughter and jests, as well as our sorrows, pains, griefs and fears. Through it, in particular, we think, see, hear and distinguish the ugly from the beautiful, the bad from the good, the pleasant from the unpleasant, in some cases using custom as a test, in others perceiving them from their utility. It is the same thing which makes us mad or delirious, inspires us with dread and fear, whether by night or by day, brings sleeplessness, inopportune mistakes, aimless anxieties, absent-mindedness, and acts that are contrary to habit.
Hippocrates of Cos (460-380 BC)
in Velmans, Max (2002) How could conscious experiences affect brains? Journal of Consciousness Studies 9(11) 3-29 [HTML]